St-Pierre-Jolys RCMP said they attended the scene of a two-vehicle collision just outside of Lorette on PTH 207.
Officers responded to the collision involving a car and a pickup truck just before 5 a.m. Sunday.
RCMP said the sole occupant of the car, a 29-year-old woman from Winnipeg, was pronounced dead at the scene.
According to RCMP, the three occupants of the pickup truck, all from Winnipeg, sustained non-life-threatening injuries. All are in stable condition.
RCMP said alcohol appears to be a factor in the collision.
The investigation is ongoing.